Konica Minolta Moves into Precision Medicine

Science is turning away from standardized treatment now that there is an understanding of how an individual’s genetic make up affects its response to different treatment. It is no surprise then, that drug development companies are looking to become top dogs in precision medicine. (“Precision medicine” is defined by the National Institutes of Health as medical care designed to optimize efficiency or therapeutic benefit for particular groups of patients, especially by using genetic or molecular profiling.) Success in precision medicine is dependent upon biomarkers that lend insight into a therapy’s efficacy. One simply cannot exist without the other, and for this reason,... Read More »

Bioverativ Starts Making Deals

In February, Biogen Inc. (NASDAQ: BIIB) completed the previously announced spin-off of its global hemophilia business. The new company, known as Bioverativ (NASDAQ: BIVV), is an independent, publicly traded global biotechnology company focused on hemophilia and other rare blood disorders. Bioverativ went on to announce the largest biotech deal of May 2017. On May 22, it acquired privately held True North Therapeutics for an upfront payment of $400 million plus assumed cash. True North investors are eligible to receive additional payments of up to $425 million contingent on the achievement of future development, regulatory and sales milestones of its lead product. Based in... Read More »

Health Care Deals Slide in April 2017

April usually doesn’t feel like February, at least, weather-wise. As far as healthcare mergers and acquisitions go, however, deal volume in April 2017 (103 deals) feels a lot like February’s deal volume (102). The chart below shows the clear winners and losers in April 2017. Deal volume was down 29% compared with the previous month (March, 145 deals), and slid 12% compared with the year before (April 2016, 141 deals). Healthcare services deal volume accounted for just 50% of April’s preliminary total. The services sectors typically account for higher percentages than the technology sectors (although that trend is reversed when it comes to dollar volume). The services side... Read More »

Q1:17 Biotechnology Deals Keep Climbing

Biotechnology deal activity has climbed steadily over the past five quarters. The sector reached 62 transactions in Q1:17, an increase of 13% over the previous quarter and up 94% year-over-year. The total is 31% of the 203 deals announced in the previous 12 months. M&A in this sector will remain active for years to come, as pharmaceutical companies that have abandoned their own R&D turn to buying up smaller biotechs with promising clinical-stage compounds. The 21st Century Cures Act also benefits this sector, with its billions of dollars in financing for both the “Cancer Moonshot” and the BRAIN Initiative. In the first quarter, 20 of the 62 transactions involved the purchase of an... Read More »

Where Have All the Big Pharma Deals Gone?

The Pharmaceutical sector has experienced a dearth of big deals so far this year. In Q1:16, 40 transactions with pharmaceutical targets were announced, for a total of $46.2 billion. In the first quarter of 2017 (through March 28), only 24 deals (-40%) for pharmaceutical targets have been announced, with a combined total of $10.1 billion (-78%). One factor behind the drop in deals is obvious. The sector came under legislative and consumer scrutiny during the presidential election in 2016, as candidates Hillary Clinton and Donald Trump each decried high prices charged by drug manufacturers, and each vowed to do something about it once elected. President Trump repeated his campaign promise to... Read More »

Cerulean Pharma Shifts its Focus to Women’s Health

Cerulean Pharma Inc. (NASDAQ:CERU), a clinical-stage company that develops nanoparticle-drug conjugates (NDCs), sold off its lead assets and is transitioning its focus from oncology to women’s health. The company announced on February 1, 2017 that it had hired investment bank Aquilo Partners, L.P., as its financial advisor to assist in a comprehensive review of strategic alternatives to maximize stockholder value. Then, on March 20, 2017, it announced that it had entered a stock purchase agreement with privately-held Daré Bioscience, in which Daré will own between 51% and 70% of the combined company. Daré Bioscience is a California-based, clinical-stage pharmaceutical company that develops... Read More »