OneOncology, based in Orlando, Florida, announced On June 2 the purchase of The START Center for Cancer Care for an undisclosed price. 

OneOncology is a national network of independent community oncologists who assist partner practices in expanding their cancer care services. The company’s 1,000 cancer care providers care for approximately 615,000 patients at more than 339 sites nationwide. In April 2023, OneOncology was acquired by TPG Capital and Cencora (formerly known as AmerisourceBergen) from General Atlantic

The START Center for Cancer Care has 37 physicians, seven advanced practice providers and 328 employees caring for 30,000 patients annually at six clinics in San Antonio and Boerne, Texas. The START Center provides patients with comprehensive services along the cancer care continuum including subspecialty care, surgery, chemotherapy, radiation therapy, immunotherapy, integrative therapies, in-house pharmacy, lab services and genetic testing. 

The practice is also the home of The START Center for Cancer Research, a global leader in early phase oncology clinical trials. In March, The START Center for Cancer Research acquired Carolina Urologic Research Center, a clinical trials company based in Myrtle Beach, South Carolina. 

By joining the OneOncology platform, The START Center for Cancer Care will maintain its independence and have access to a comprehensive platform of clinical, operational and technological resources that support physician-led cancer care. The financial terms were not disclosed. 

According to data captured in the LevinPro HC database, this marks the 191st Physician Medical Group acquisition of 2025 and the fourth in the oncology specialty. This also represents OneOncology’s third transaction of the year; previously, it acquired two practices with locations in New York, Indiana and Idaho.