Last Friday, the Biotech sector, represented by the Nasdaq Biotechnology index (NASDAQ: IBB), officially entered a correction phase, based on a 14% drop in valuations since July 20. That could put a damper on a sector that’s seen tremendous M&A activity in 2015, with 117 deals announced so far (vs. 136 total in 2014), and nearly $40 billion in spending (well up from the $21 billion spent in 2014). While the AbbVie‘s (NYSE: ABBV) $21 billion takeover of Pharmacyclics (NASDAQ: PCYC) has a lot to do with the large total, billion-dollar deals haven’t been uncommon. Take a look.

TargetAcquirerPrice
PharmacyclicsAbbVie$21.0 billion
NPS PharmaceuticalsShire plc$5.2 billion
Auspex PharmaceuticalsTeva Pharmaceuticals$3.2 billion
Therakos, Inc. Mallinckrodt plc$1.33 billion
Polypore's separations business3M Company$1.0 billion
Source: The Health Care M&A Information Source